英 [laʊs ʌp] 美 [laʊs ʌp]
搞砸：指把事情搞得一团糟。
... 愚弄某人 make a jest of 弄糟;毁坏 louse up 嘲弄;取笑 make fun of ...
... mishandle粗暴对待 louse up破坏 bollocks胡说 ...
毁坏；弄糟
I don't know how to deal with Jack. He is indeed a trouble maker. He has louse up my business several times.
我不知道怎么对付杰克，他是在是个捣蛋鬼，好几次把我的事情弄成一团糟。
Their liens will louse up your title to property and devastate your credit rating.
FORBES: Render Unto Caesar - Mormon Tithe Not A Necessary Expense In IRS Collection Case
Some day it will be a study in how states can louse up anything, and how states failing to act together can louse up everything.
FORBES: Bi-Partisan Entitlement Reduction Efforts Focusing On Deep Cuts To Medicaid
Or will we assert our inalienable right to louse things up, each in our own individual way?
CNN: Behold the?all-seeing, self-parking, safety-enforcing, networked car