From a practical viewpoint, I'd advise you not to go.
从实际角度考虑，我劝你不要去。
From a practical point of view, it isn't a good place to live.
实际一点看，这里不是理想的住处。
He had a practical outlook on life.
他的人生观很实际。
What's the practical value of a (c)(4) designation if it doesn't generate writeoffs for its donors?
It's a practical guide (or guerrilla manual, as Kawasaki might say) for starting a business and keeping it going long enough to have a shot at real success.
Second, please stop comparing Twitter to Zynga (which is a game publisher) and Groupon (which is an accounting practical joke).